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Can You Clean A Ua With Blea H

Urine cariosity: can bleach be used to mask MDMA apply?

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Abstract

Concerns regarding specimen integrity have long been a major issue of urine drug testing due to acts of urine adulteration. At a high concentration, in vitro urine adulteration using sodium hypochlorite (bleach) produced faux-negative results for 3,iv-methylenedioxymethamphetamine (MDMA) in CEDIA ® immunoassay screening with strong negative readings. However, these strong negative readings may deed as a alert sign for further investigation of the sample where the detection of a unique mark in the form of N-chloroMDMA will suggest urine adulteration via bleach. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) identified N-chloroMDMA is a major product formed betwixt hypochlorite and MDMA in urine. N-ChloroMDMA was found stable at 4 °C for at least 10 h, just decomposed over time at room temperature (twenty °C) with MDMA being identified as one of its principal decomposition products.

Graphical abstract: Urine adulteration: can bleach be used to mask MDMA use?

  • This commodity is function of the themed collection: Security and Forensics

This article is Open Access

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Article data

DOI
https://doi.org/x.1039/C3AY40543E

Article type
Paper

Submitted
01 Apr 2022

Accustomed
thirteen Jun 2022

First published
14 Jun 2022

This article is Open up Access
Creative Commons BY-NC license

Anal. Methods , 2022, 5, 3948-3955

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Urine adulteration: can bleach be used to mask MDMA utilise?

A. Q. N. Pham, T. Kelly and South. Fu, Anal. Methods, 2022,5, 3948 DOI: 10.1039/C3AY40543E

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Source: https://pubs.rsc.org/en/content/articlelanding/2013/ay/c3ay40543e

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